Eosinophilic Inflammation

澳门葡京赌博游戏的目标是解决由嗜酸性粒细胞炎症引起的炎症性疾病患者的未满足需求

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澳门葡京赌博游戏致力于发现嗜酸性粒细胞炎症及其对一系列疾病的影响

澳门葡京赌博游戏在呼吸系统护理方面拥有50年的传统,并遵循从呼吸系统疾病到免疫驱动疾病领域的共同途径和潜在疾病驱动因素的科学,以更好地了解嗜酸性粒细胞作为一系列潜在的衰弱性炎症疾病的关键效应细胞的重要作用.

一些嗜酸性粒细胞驱动的疾病有有限的或没有批准的治疗方案, creating a significant unmet need for innovative medicines. 澳门葡京赌博游戏现在知道一个叫做嗜酸性粒细胞炎症的过程可能是导致这些疾病的嗜酸性粒细胞募集和激活的原因. Backed by a growing body of evidence, 澳门葡京赌博游戏致力于促进对嗜酸性粒细胞在炎症性疾病中的作用的理解 呼吸 & 免疫学,目的是改善诊断、病人转诊和及时、适当的治疗.
 


What is eosinophilic inflammation?

当炎症性疾病中存在嗜酸性粒细胞时,嗜酸性炎症可能是病因. 对嗜酸性粒细胞炎症的了解将有助于提高人们的认识,即看似不同的疾病实际上有一个共同的原因——嗜酸性粒细胞炎症——将它们联系在一起.




病人宪章


嗜酸性粒细胞患者组织和临床医生的代表组成了《澳门葡京赌博游戏》,鼓励对患有嗜酸性粒细胞相关疾病的患者进行护理改革。. 它概述了四项优质护理原则和减轻患者负担的明确步骤:

  1. Greater awareness of EADs for patients, 护理人员, health care professionals, 以及普通大众
  2. Timely and accurate diagnosis
  3. Access to an appropriate multidisciplinary team
  4. Access to safe and effective treatment options

By addressing the need for more education among patients, healthcare professionals, 公众, 《澳门葡京网赌游戏》继续支持为全世界数百万受嗜酸性粒细胞疾病影响的人提供改进的治疗方案1.





Some of the eosinophil-driven diseases

澳门葡京赌博游戏目前正在探索可能由嗜酸性粒细胞炎症引起的广泛疾病的潜在药物,以及未满足的医疗需求仍然很大的地方, 在某些情况下, where we see an increasing prevalence.


Abdulhammed_Babatunde

大疱性类天疱疮(BP)

Abdulhammed_Babatunde

Eosinophilic Asthma (EA)


Abdulhammed_Babatunde

Chronic rhinosinusitis with nasal polyp (CRSwNP)

Abdulhammed_Babatunde

Eosinophilic Granulomatosis with Polyangiitis (EGPA)

Abdulhammed_Babatunde

Hypereosinophilic Syndrome (HES)


参考文献。

1. 杰克逊,维. J.阿库托塔,P.安德拉达斯,R.等。. Improving care in eosinophil-associated diseases: A Charter. 治疗进展. 2022; 39 (6): 2323–2341.

2. Ramirez GA, Yacoub MR, Ripa M, 等. Eosinophils from physiology to disease: a comprehensive review. 生物医学研究中心. 2018; 9095275.

3. National Organisation for Rare Disorders. 大疱的类天疱疮. Available at: http://rarediseases.org/rare-diseases/bullous-pemphigoid. [Last accessed: July 2023].

4. 文策尔SE. 成人严重哮喘. Am J Respir Crit Care Med. 2005; 172: 149-160.

5. Coumou H, Bel EH. Improving the diagnosis of eosinophilic asthma. 呼吸医学专家. 2016;10(10): 1093-1103.

6. 特里维迪SG,劳埃德CM. Eosinophils in the pathogenesis of allergic airways disease. 细胞与生命科学. 2007; 64 (10): 1269-1289. 

7. American Partnership for Eosinophilic Disorders. Eosinophilic Granulomatosis with Polyangiitis (EGPA). Available at: http: apfed.org/about-ead/eosinophilic-granulomatosis-with-polyangiitis/. [Last accessed: July 2023].

8. Baldini C, Talarico R, Della Rossa A, Bombardieri S. Clinical Manifestations and Treatment of Churg-Strauss Syndrome. Rheum Dis clinn Am. 2010; 36: 527-543. 

9. American Partnership for Eosinophilic Disorders. Hypereosinophilic Syndromes. Available at: http://apfed.org/about-ead/hypereosinophilic-syndrome/. [Last accessed: July 2023].

10. American Partnership for Eosinophilic Disorders. APFED Hypereosinophilic Syndromes Brochure. 2017年12月. Available at: http://apfed.org/wp-content/uploads/2017/12/APFED_HES_bro_final.pdf. [Last accessed: July 2023].

11. Bachert C, Akdis CA. Phenotypes and Emerging Endotypes of Chronic Rhinosinusitis. J Allergy Clin Immunol Pract. 2016; 4 (4): 621-628.

12. 牛顿JR, Ah-See KW. A review of nasal polyposis. 临床风险管理. 2008; 4 (2): 507-512.

13. Fujieda S Imoto Y, Kato Y, . Eosinophilic chronic rhinosinusitis. 变态反应学Int. 2019; 68 (4): 403-412.

14. 霍普金斯C. Chronic Rhinosinusitis with Nasal Polyp. [英]医学. 2019; 381 (1): 55-63.

15. Stevens WW, Schleimer RP, Kern RC. Chronic Rhinosinusitis with Nasal Polyp. J Allergy Clin Immunol Pract. 2016; 4 (4): 565-572.

16. Abdalla S, Alreefy H, 霍普金斯C. 在英格兰和威尔士国家前瞻性审计中,接受慢性鼻窦炎手术的患者鼻窦结局试验(SNOT-22)症状的患病率. 中国Otolaryngol. 2012; 37 (4): 276-282.


Veeva ID: Z4-55874
Date of preparation: August 2023